New Bron Solution Ace (新ブロン液エース): ingredients, dose and warnings in English
New Bron Solution Ace (新ブロン液エース) is sold in Japan as a designated class 2 medicine: the box reads 第②類医薬品. The maker writes the name in English as NEW BRON SOLUTION - ACE. In 60 mL: Dihydrocodeine Phosphate 30 mg, Guaifenesin 170 mg, Chlorpheniramine Maleate 12 mg, Anhydrous Caffeine 62 mg. The package insert sets the adult dose at 10 mL, 3 times a day, and up to 6 times a day depending on the situation, for ages 12 and over.
第②類医薬品 · Designated class 2要確認 · Shop checks first
What is in New Bron Solution Ace
The package insert lists 4 active ingredients in 60 mL. The middle column is how each one is written on the Japanese box.
| Ingredient | Name on the box | Amount |
|---|---|---|
| Dihydrocodeine Phosphate | ジヒドロコデインリン酸塩 | 30 mg |
| Guaifenesin | グアイフェネシン | 170 mg |
| Chlorpheniramine Maleate | クロルフェニラミンマレイン酸塩 | 12 mg |
| Anhydrous Caffeine | 無水カフェイン | 62 mg |
Additives, as written on the package insert (Japanese)
果糖ブドウ糖液糖、アルコール、プロピレングリコール、塩化Na、クエン酸、安息香酸Na、パラベン、エチルバニリン、カラメル、バニリン、l-メントール、香料
The maker publishes an English package insert for NEW BRON SOLUTION - ACE: SSP: NEW BRON SOLUTION - ACE (English package insert). This page translates the current Japanese package insert on PMDA.
Source: PMDA (Pharmaceuticals and Medical Devices Agency) — 新ブロン液エース: package insert (添付文書) · SSP — NEW BRON SOLUTION - ACE: English package insert
What the package insert lists it for
The approved wording of the Japanese package insert, translated. It is what the product is sold for, not advice on what to take.
- Cough, phlegm
The dose, as written on the package insert
Translated line by line from the directions and dosage (用法・用量) section.
- Dihydrocodeine Phosphate per dose
- 5 mg
- Adult dose
- 10 mL
- Doses a day
- 3, up to 6
- Age
- 12 and over
- Measure the following single dose with the measuring cup provided, and in each case take it 3 times a day after meals. Depending on the situation, it is acceptable to take it up to 6 times a day, but in this case take doses at least 4 hours apart.
| Age | Single dose |
|---|---|
| Adults (15 and over) | 10 mL |
| 12 to 14 | 6.6 mL |
| Under 12 | Do not take |
- * Rinse the measuring cup well with water after each use, and store it hygienically together with this medicine.
Notes on the directions
- (1) Follow the directions and dosage exactly.
- (2) When giving it to children, have them take it under the guidance and supervision of a parent or guardian.
Do not
The package insert opens with what you must not do.
(If you do not follow these, your current symptoms may get worse, and side effects or accidents become more likely.)
1. Do not take it if you are one of the following people
- Children under 12.
2. Do not use any of the following medicines while taking this medicine
- Other cough medicines, cold medicines, sedatives, oral medicines containing antihistamines, etc. (oral medicines for rhinitis, motion sickness medicines, allergy medicines, sleep aids and sedatives, etc.)
3. Do not drive or operate machinery after taking it
- (Drowsiness etc. may occur.)
4. Women who are breastfeeding: do not take this medicine, or avoid breastfeeding if you take it
5. Do not take an excessive amount, and do not keep taking it for a long time
- (Lethargy, a feeling of prostration, etc. may occur.)
Ask a doctor, pharmacist or registered salesperson
The package insert says to ask for advice in these cases.
1. If you are one of the following people, ask a doctor, pharmacist or registered salesperson for advice before taking it
- (1) People who are receiving treatment from a doctor.
- (2) Women who are pregnant or think they may be pregnant.
- (3) People who have had allergic symptoms caused by medicines etc.
- (4) People who have the following symptoms. High fever, difficulty urinating
- (5) People who have been diagnosed with the following. Glaucoma, respiratory dysfunction, obstructive sleep apnoea syndrome, obesity
2. If the following symptoms appear after taking it, they may be side effects, so stop taking it immediately and ask a doctor, pharmacist or registered salesperson for advice, taking this box with you
Possible side effects, by part of the body
- Skin
- rash/redness, itching
- Digestive system
- nausea/vomiting, loss of appetite
- Nervous system
- dizziness
- Urinary system
- difficulty urinating
- In rare cases the following serious symptoms may occur. If they do, see a doctor immediately.
Rare but serious symptoms: name and signs
- Aplastic anaemia
- bruises, nosebleeds, bleeding gums, fever, the skin and mucous membranes looking pale, a feeling of fatigue, palpitations, shortness of breath, feeling unwell and light-headed, blood in the urine, etc. appear.
- Agranulocytosis
- sudden high fever, chills, sore throat, etc. appear.
- Respiratory depression
- shortness of breath, difficulty breathing, etc. appear.
3. The following symptoms may appear after taking it, so if these symptoms continue or get worse, stop taking it and ask a doctor, pharmacist or registered salesperson for advice, taking this box with you
- Constipation, dry mouth, drowsiness
4. If your symptoms do not improve after taking it 5 to 6 times, stop taking it and ask a doctor, pharmacist or registered salesperson for advice, taking this box with you
Who can sell it in Japan
The New Bron Solution Ace box carries the class 第②類医薬品, which decides who may sell it.
- On the box
- 第②類医薬品 (Designated class 2). The box reads 第2類医薬品 with the 2 in a square, or 第②類医薬品.
- Who can sell it
- A pharmacist or a registered salesperson may sell it.
要確認: the shop checks before selling this one.New Bron Solution Ace contains Dihydrocodeine Phosphate. From 1 May 2026, medicines taken by mouth with this ingredient are designated abuse-prevention medicines (指定濫用防止医薬品).
- The five classes on Japanese medicine boxes, side by side
- What the shop checks before selling New Bron Solution Ace: age, pack size and ID
Source: e-Gov law search (Digital Agency, Japan) — Pharmaceutical and Medical Device Act (医薬品医療機器等法), current text · e-Gov law search (Digital Agency, Japan) — Enforcement Regulations of the Pharmaceutical and Medical Device Act (施行規則), current text · Ministry of Health, Labour and Welfare — Designated class 2 medicines (指定第２類医薬品について) · Ministry of Health, Labour and Welfare — Designated abuse-prevention medicines, Notice No. 32 of 2026 (告示第32号) · Ministry of Health, Labour and Welfare — Quantity for designated abuse-prevention medicines, Notice No. 33 of 2026 (告示第33号) · Ministry of Health, Labour and Welfare — Selling designated abuse-prevention medicines (医薬発1226第16号, 26 December 2025) · Ministry of Health, Labour and Welfare — Q&A on selling designated abuse-prevention medicines (30 January 2026)
Taking it home
New Bron Solution Ace contains Dihydrocodeine Phosphate. South Korea, Taiwan, mainland China and Hong Kong each have official rules on this ingredient.
Frequently asked questions
How much Dihydrocodeine Phosphate is in New Bron Solution Ace?
5 mg in a dose of 10 mL, according to the Japanese package insert. The package insert lists 30 mg in 60 mL.
How much New Bron Solution Ace can an adult take in a day?
The package insert sets the adult dose at 10 mL, 3 times a day, and up to 6 times a day depending on the situation. Doses are at least 4 hours apart.
Can children take New Bron Solution Ace?
The package insert gives doses from age 12 and says it is not to be taken below that age.
Do I need a pharmacist to buy New Bron Solution Ace?
New Bron Solution Ace is a designated class 2 medicine (第②類医薬品). A pharmacist or a registered salesperson may sell it.
Why does the shop check before selling New Bron Solution Ace?
It contains Dihydrocodeine Phosphate, one of the 8 ingredients that make a medicine taken by mouth a designated abuse-prevention medicine (指定濫用防止医薬品) from 1 May 2026. The shop gives the information in writing and checks what you have bought there and at other shops.
What is New Bron Solution Ace called in Japanese?
新ブロン液エース. The New Bron Solution Ace box also carries the class 第②類医薬品.
Related items
Package insert in Japanese: PMDA
Sources for this page
- PMDA (Pharmaceuticals and Medical Devices Agency) 新ブロン液エース: package insert (添付文書)checked October 3, 2026
- SSP NEW BRON SOLUTION - ACE: English package insertchecked October 3, 2026
- e-Gov law search (Digital Agency, Japan) Pharmaceutical and Medical Device Act (医薬品医療機器等法), current textchecked October 3, 2026
- e-Gov law search (Digital Agency, Japan) Enforcement Regulations of the Pharmaceutical and Medical Device Act (施行規則), current textchecked October 3, 2026
- Ministry of Health, Labour and Welfare Designated class 2 medicines (指定第２類医薬品について)checked October 3, 2026
- Ministry of Health, Labour and Welfare Designated abuse-prevention medicines, Notice No. 32 of 2026 (告示第32号)checked October 3, 2026
- Ministry of Health, Labour and Welfare Quantity for designated abuse-prevention medicines, Notice No. 33 of 2026 (告示第33号)checked October 3, 2026
- Ministry of Health, Labour and Welfare Selling designated abuse-prevention medicines (医薬発1226第16号, 26 December 2025)checked October 3, 2026
- Ministry of Health, Labour and Welfare Q&A on selling designated abuse-prevention medicines (30 January 2026)checked October 3, 2026
Compiled by Japan Japan !! · Updated October 3, 2026