Cabagin Kowa α Plus (キャベジンコーワαプラス): ingredients, dose and warnings in English
Cabagin Kowa α Plus (キャベジンコーワαプラス) is sold in Japan as a class 2 medicine: the box reads 第2類医薬品. In 6 tablets: Methylmethionine Sulfonium Chloride 150.0 mg, Sodium Bicarbonate 600.0 mg, Magnesium Hydroxide 210.0 mg, Precipitated Calcium Carbonate 1340.0 mg, Scopolia Extract 3-fold Powder 90.0 mg, Perilla Herb Dry Extract 20.0 mg and 4 more. The package insert sets the adult dose at 2 tablets, 3 times a day, for ages 8 and over.
第2類医薬品 · Class 2
What is in Cabagin Kowa α Plus
The package insert lists 10 active ingredients in 6 tablets. The middle column is how each one is written on the Japanese box.
| Ingredient | Name on the box | Amount |
|---|---|---|
| Methylmethionine Sulfonium Chloride | メチルメチオニンスルホニウムクロリド | 150.0 mg |
| Sodium Bicarbonate | 炭酸水素ナトリウム | 600.0 mg |
| Magnesium Hydroxide | 水酸化マグネシウム | 210.0 mg |
| Precipitated Calcium Carbonate | 沈降炭酸カルシウム | 1340.0 mg |
| Scopolia Extract 3-fold Powder *(30.0 mg as scopolia extract) | ロートエキス3倍散 | 90.0 mg |
| Perilla Herb Dry Extract *(180.0 mg as perilla herb) | ソヨウ乾燥エキス | 20.0 mg |
| Magnolia Bark Dry Extract *(180.0 mg as magnolia bark) | コウボク乾燥エキス | 15.0 mg |
| Powdered Swertia Herb | センブリ末 | 30.0 mg |
| Biodiastase 2000 * | ビオヂアスターゼ2000 | 24.0 mg |
| Lipase AP12 * | リパーゼAP12 | 15.0 mg |
* No official English name in the Japanese Accepted Names (JAN) database or the Japanese Pharmacopoeia. The English here describes the Japanese name; the name on the box is in the middle column.
Additives, as written on the package insert (Japanese)
ヒドロキシプロピルセルロース,硬化油,カルメロースカルシウム(CMC-Ca),トウモロコシデンプン,ステアリン酸マグネシウム,ステアリン酸グリセリン,ステアリン酸ポリオキシル,セラック,タルク,ケイヒ,ポリビニルアルコール(部分けん化物),セルロース,二酸化ケイ素,l-メントール,デキストリン
The maker publishes an English package insert for CABAGIN KOWA α PLUS: Kowa: CABAGIN KOWA α PLUS (English package insert). This page translates the current Japanese package insert on PMDA.
Source: PMDA (Pharmaceuticals and Medical Devices Agency) — キャベジンコーワαプラス: package insert (添付文書) · Kowa — CABAGIN KOWA α PLUS: English package insert
What the package insert lists it for
The approved wording of the Japanese package insert, translated. It is what the product is sold for, not advice on what to take.
- Stomach discomfort, weak stomach, heavy stomach, stomach pain, overeating, drinking too much, heartburn, nausea (queasiness, queasy stomach, queasiness from a hangover/feeling ill after drinking, feeling like vomiting, feeling sick), vomiting, loss of appetite, indigestion, excess stomach acid, belching, a feeling of something stuck in the chest, promotion of digestion, a bloated feeling in the stomach/abdomen, a heavy feeling in the stomach
The dose, as written on the package insert
Translated line by line from the directions and dosage (用法・用量) section.
- Methylmethionine Sulfonium Chloride per dose
- 50 mg
- Adult dose
- 2 tablets
- Doses a day
- 3
- Age
- 8 and over
- Take the following amount after each meal with water or warm water.
| Age | Single dose | Number of doses |
|---|---|---|
| Adults (15 and over) | 2 tablets | 3 times a day |
| 8 and over but under 15 | 1 tablet | 3 times a day |
| Children under 8 | Do not take |
Notes on the directions
- (1) Follow the directions and dosage exactly.
- (2) When giving it to children, have them take it under the guidance and supervision of a parent or guardian.
Do not
The package insert opens with what you must not do.
(If you do not follow these, your current symptoms may get worse, and side effects become more likely)
1. Do not take the following medicines while taking this medicine
- Gastrointestinal pain and spasm relievers
2. Women who are breastfeeding: do not take this medicine, or avoid breastfeeding if you take it
- (It may pass into breast milk and make the baby's pulse faster.)
Ask a doctor, pharmacist or registered salesperson
The package insert says to ask for advice in these cases.
1. If you are one of the following people, ask a doctor, pharmacist or registered salesperson for advice before taking it
- (1) People who are receiving treatment from a doctor.
- (2) Women who are pregnant or think they may be pregnant.
- (3) Older people.
- (4) People who have had allergic symptoms caused by medicines etc.
- (5) People who have the following symptoms. Difficulty urinating
- (6) People who have been diagnosed with the following. Kidney disease, heart disease, glaucoma, thyroid dysfunction
2. If the following symptoms appear after taking it, they may be side effects, so stop taking it immediately and ask a doctor, pharmacist or registered salesperson for advice, taking this outer box with you
Possible side effects, by part of the body
- Skin
- rash/redness, itching
3. The following symptoms may appear after taking it, so if these symptoms continue or get worse, stop taking it and ask a doctor, pharmacist or registered salesperson for advice, taking this outer box with you
- Dry mouth
4. If your symptoms do not improve after taking it for about 2 weeks, stop taking it and ask a doctor, pharmacist or registered salesperson for advice, taking this outer box with you
Other precautions
- It may become harder for breast milk to come out.
Who can sell it in Japan
The Cabagin Kowa α Plus box carries the class 第2類医薬品, which decides who may sell it.
- On the box
- 第2類医薬品 (Class 2). The box reads 第2類医薬品.
- Who can sell it
- A pharmacist or a registered salesperson may sell it.
Source: e-Gov law search (Digital Agency, Japan) — Pharmaceutical and Medical Device Act (医薬品医療機器等法), current text · e-Gov law search (Digital Agency, Japan) — Enforcement Regulations of the Pharmaceutical and Medical Device Act (施行規則), current text
Taking it home
Frequently asked questions
How much Methylmethionine Sulfonium Chloride is in Cabagin Kowa α Plus?
50 mg in a dose of 2 tablets, according to the Japanese package insert. The package insert lists 150.0 mg in 6 tablets.
How much Cabagin Kowa α Plus can an adult take in a day?
The package insert sets the adult dose at 2 tablets, 3 times a day.
Can children take Cabagin Kowa α Plus?
The package insert gives doses from age 8 and says it is not to be taken below that age.
Do I need a pharmacist to buy Cabagin Kowa α Plus?
Cabagin Kowa α Plus is a class 2 medicine (第2類医薬品). A pharmacist or a registered salesperson may sell it.
What is Cabagin Kowa α Plus called in Japanese?
キャベジンコーワαプラス. The Cabagin Kowa α Plus box also carries the class 第2類医薬品.
Related items
Package insert in Japanese: PMDA
Sources for this page
- PMDA (Pharmaceuticals and Medical Devices Agency) キャベジンコーワαプラス: package insert (添付文書)checked October 3, 2026
- Kowa CABAGIN KOWA α PLUS: English package insertchecked October 3, 2026
- e-Gov law search (Digital Agency, Japan) Pharmaceutical and Medical Device Act (医薬品医療機器等法), current textchecked October 3, 2026
- e-Gov law search (Digital Agency, Japan) Enforcement Regulations of the Pharmaceutical and Medical Device Act (施行規則), current textchecked October 3, 2026
Compiled by Japan Japan !! · Updated October 3, 2026